Best CBD Oil for Anxiety and Stress in 2021

Written by 
Gleb Oleinik, CBD Journalist.
|Check IconMedically reviewed by 
Eloise Theisen, RN, MSN, AGPCNP-BC.
|Last Updated:
* Leafreport may receive compensation. Here’s how we make money.
* Our review is consumer-focused only and we do not check or take a stand regarding medical effects.
* Statements regarding CBD products have not been evaluated by the Food and Drug Administration.
* Please advise your physician prior to each use of CBD.

You’re probably familiar with cannabidiol (CBD), one of the main active components of cannabis. Unlike tetrahydrocannabinol (THC), CBD doesn’t cause intoxication.

CBD products are used by a growing number of people to help with a wide variety of health issues, including anxiety.

Although more studies are needed, research has shown that CBD has potent anxiolytic (anxiety-reducing) effects that can help with occasional anxiety as well as specific anxiety disorders.

But with so many products to choose from, it can be tough to make a choice. That’s why we compared different brands to find the best CBD products for anxiety.

What does science say about CBD and anxiety?

Multiple clinical studies have shown that CBD can relieve various types of anxiety:

  • In a 2019 Japanese study, CBD oil decreased anxiety in teenagers with social anxiety disorder (SAD) and avoidant personality disorder (AVPD)
  • In a 2011 Brazilian study, CBD capsules reduced anxiety induced by public speaking in people with SAD
  • In another 2019 study out of Colorado, CBD capsules improved anxiety in people with sleep or anxiety disorders
  • A 2020 review paper of all the available evidence on the use of CBD for anxiety concluded that “CBD has a promising role as alternative therapy in the management of anxiety disorders

Overall, the findings are quite promising and confirm anecdotal reports of CBD users. Still, researchers stress the need for further high quality studies to figure out the best CBD dosage for anxiety and other specifics.

How we chose these products

Our team of medical doctors, nutritionists, and other health experts chose these products based on their quality, transparency, price, and other criteria. For example, all of the products we recommend are tested by a third party lab to verify their potency and safety.

We also consider factors relevant to anxiety. For example, we suggest THC free options because some people are sensitive to THC and may feel anxious from a large dose of a full spectrum product. Check here for more details on how we choose products.

We also use an objective ranking system that rates brands and products out of 100 points.

#1 Bests

Leafreport’s picks of the Best CBD oils

Full Spectrum Hemp CBD Oil 3000mg
CBD Amount Score IconTotal CBD 3000 mg
Available Bottle Sizes Score IconBottle Size 50 ml
Potency Score IconPotency60 mg/ml
90
$239 $0.08 mg/CBD
Visit Site
Broad Spectrum CBD Oil Tincture - 1000mg - 30ml
CBD Amount Score IconTotal CBD 1000 mg
Available Bottle Sizes Score IconBottle Size 30 ml
Potency Score IconPotency33.33 mg/ml
82
$55 $0.06 mg/CBD
Visit Site
CBD Oil 150Mg CBD/ml (Strong)
CBD Amount Score IconTotal CBD 1500 mg
Available Bottle Sizes Score IconBottle Size 10 ml
Potency Score IconPotency150 mg/ml
95
$150.5 $0.1 mg/CBD
Visit Site
Classic High Potency CBD Tincture 3000mg
CBD Amount Score IconTotal CBD 3000 mg
Available Bottle Sizes Score IconBottle Size 60 ml
Potency Score IconPotency50 mg/ml
92
$70 $0.02 mg/CBD
Visit Site
Plus CBD Softgel Capsules 30ct 15MG Gold Formula
CBD Amount Score IconTotal CBD 450 mg
Available Bottle Sizes Score IconUnits 30 ml
Potency Score IconPotency15 mg/unit
90
$39.99 $0.09 mg/CBD
Visit Site
CBD Chews
CBD Amount Score IconTotal CBD 750 mg
Available Bottle Sizes Score IconUnits 30 ml
Potency Score IconPotency25 mg/unit
87
$59 $0.08 mg/CBD
Visit Site
Platinum Rose – CBD Terpenes Oil - 500 mg
CBD Amount Score IconTotal CBD 500 mg
Available Bottle Sizes Score IconBottle Size 30 ml
Potency Score IconPotency16.67 mg/ml
82
$69.99 $0.14 mg/CBD
Visit Site

Our picks

Best Overall — NuLeaf Naturals

Nuleaf Naturals Full Spectrum Hemp CBD Oil 3000mg

Overall Score
Product Review
90out of 100
$239 $0.08 mg/CBD
Visit Site
Score Breakdown
Quality Assurance
40/40
Hemp Quality
15/20
Extract Type
20/20
Additional ingredients
7/10
Price
8/10
CBD Amount Score IconTotal CBD 3000 mg
Available Bottle Sizes Score IconBottle Size 50 ml
Potency Score IconPotency60 mg/ml

Best Vape Product — CBDfx Terpene Vape Liquid

CBDfx Platinum Rose – CBD Terpenes Oil - 500 mg

Overall Score
Product Review
82out of 100
$69.99 $0.14 mg/CBD
Visit Site
Score Breakdown
Quality Assurance
40/40
Hemp Quality
15/20
Extract Type
12/20
Additional ingredients
7/10
Price
8/10
CBD Amount Score IconTotal CBD 500 mg
Available Bottle Sizes Score IconBottle Size 30 ml
Potency Score IconPotency16.67 mg/ml

For those who need immediate anxiety relief, vaping CBD can be a fast-acting alternative to CBD oil. Our top pick is the terpene vape liquid from CBDfx, which comes in four flavors and two potencies: 500 mg (17 mg/ml) and 1000 mg (33 mg/ml).

 

It contains a blend of terpenes inspired by popular cannabis strains. CBDfx also sells a vape kit if you don’t have a vape.

 

Quality AssuranceIcon
Quality Assurance
40/40

Third-party tests confirm that this vape juice contains the advertised amount of CBD.

 

Hemp QualityIcon
Hemp Quality
15/20

CBDfx uses organic Kentucky hemp to make its products.

 

Extract TypeIcon
Extract Type
12/20

CBDfx’s vape juice contains pure CBD isolate.

 

Additional ingredientsIcon
Additional ingredients
7/10

This vape juice contains a blend of terpenes from one of four cannabis strains. Terpenes add flavor and may have beneficial properties

 

PriceIcon
Price
8/10

CBDfx’s terpene vape liquid costs $0.07-0.10 per mg of CBD, which is cheaper than most CBD vape oils.

Pros: Cons:
  • High CBD potency
  • Comprehensive third party testing
  • No flavored options

Best THC Free — CBDistillery

CBDistillery Broad Spectrum CBD Oil Tincture - 1000mg - 30ml

Overall Score
Product Review
82out of 100
$55 $0.06 mg/CBD
Visit Site
Score Breakdown
Quality Assurance
34/40
Hemp Quality
15/20
Extract Type
16/20
Additional ingredients
7/10
Price
10/10
CBD Amount Score IconTotal CBD 1000 mg
Available Bottle Sizes Score IconBottle Size 30 ml
Potency Score IconPotency33.33 mg/ml

Some people, and especially those suffering from anxiety, are sensitive to THC. This means they can experience an increase in anxiety even from the small amount of THC (<0.3%) present in a full spectrum product.

For those people, we recommend the broad spectrum CBD oil from CBDistillery, which carries 33 mg of CBD per ml, for a total of 1000 mg.

 

Quality AssuranceIcon
Quality Assurance
34/40

Third party tests verify that this CBD oil is free of THC and contaminants, although it may contain more CBD than stated on the label.

 

Hemp QualityIcon
Hemp Quality
15/20

CBDistillery is a popular brand that’s certified by the U.S. Hemp Authority for adhering to high quality standards. Its tinctures are made from organic Colorado hemp.

 

Extract TypeIcon
Extract Type
16/20

This tincture is made with broad spectrum CBD, which has no THC while retaining other beneficial hemp compounds.

 

Additional ingredientsIcon
Additional ingredients
7/10

Aside from CBD, this broad spectrum CBD oil contains multiple cannabinoids.

 

PriceIcon
Price
10/10

With a price of $0.06 per mg of CBD, this CBD oil is cheaper than average.

Pros: Cons:
  • High CBD potency
  • Comprehensive third party testing
  • U.S. Hemp Authority certified
  • No flavored options

Best Potency — Endoca

Endoca CBD Oil 150Mg CBD/ml (Strong)

Overall Score
Product Review
95out of 100
$150.5 $0.1 mg/CBD
Visit Site
Score Breakdown
Quality Assurance
40/40
Hemp Quality
17/20
Extract Type
20/20
Additional ingredients
10/10
Price
8/10
CBD Amount Score IconTotal CBD 1500 mg
Available Bottle Sizes Score IconBottle Size 10 ml
Potency Score IconPotency150 mg/ml

Everyone’s ideal CBD dosage is different. If you find that you need large doses, we recommend the strong CBD oil from Endoca, one of the oldest and most respected CBD companies in the world.

This full spectrum tincture has a very high potency of 150 mg of CBD per ml, with a total of 1500 mg of CBD in the 10 ml bottle. You can choose the natural or chocolate mint flavor.

 

Quality AssuranceIcon
Quality Assurance
40/40

According to third party and in house tests, this tincture contains the correct amount of CBD and is free of pesticides and other potential contaminants.

 

Hemp QualityIcon
Hemp Quality
17/20

This CBD oil is sourced from organic Danish hemp cultivated by Endoca and the local farmers it partners with.

 

Extract TypeIcon
Extract Type
20/20

This is a high quality full spectrum CBD oil so you’re getting the most out of hemp’s benefits.

 

Additional ingredientsIcon
Additional ingredients
10/10

Our third party test study found that Endoca’s tinctures contain multiple minor cannabinoids aside from CBD, which is a great sign.

 

PriceIcon
Price
8/10

Endoca’s CBD oil costs $0.10 per mg of CBD, which is an average price point.

Pros: Cons:
  • Very high CBD potency
  • Third party and in house testing
  • Small bottle size
  • The unflavored option has a strong hemp taste

Best Value — Lazarus Naturals

Lazarus Naturals Classic High Potency CBD Tincture 3000mg

Overall Score
Product Review
92out of 100
$70 $0.02 mg/CBD
Visit Site
Score Breakdown
Quality Assurance
40/40
Hemp Quality
15/20
Extract Type
20/20
Additional ingredients
7/10
Price
10/10
CBD Amount Score IconTotal CBD 3000 mg
Available Bottle Sizes Score IconBottle Size 60 ml
Potency Score IconPotency50 mg/ml

Lazarus Naturals is our top pick for the value oriented shopper. The company’s high potency (50 mg/ml) tincture provides 3000 mg of CBD at an exceptionally low price.

 

Quality AssuranceIcon
Quality Assurance
40/40

According to third party tests, this CBD oil is free of contaminants and contains an accurate amount of CBD.

 

Hemp QualityIcon
Hemp Quality
15/20

Lazarus Naturals’ products are derived from organic hemp cultivated in central Oregon.

 

Extract TypeIcon
Extract Type
20/20

This CBD oil contains full spectrum hemp extract, the most effective form of CBD.

 

Additional ingredientsIcon
Additional ingredients
7/10

Third party potency tests show multiple cannabinoids aside from CBD, which is a sign of a high quality full spectrum extract.

 

PriceIcon
Price
10/10

Lazarus Naturals’ high potency CBD tincture costs only $0.02 per mg of CBD, which is far cheaper than the average market price. The company also offers a 60% discount for veterans, people with disabilities, and low income families.

Pros: Cons:
  • Exceptionally low prices
  • High CBD potency
  • Comprehensive third party testing
  • Multiple flavors and sizes
  • Lacks higher potencies

Best Capsules — PlusCBD 

PlusCBD Oil Plus CBD Softgel Capsules 30ct 15MG Gold Formula

Overall Score
Product Review
90out of 100
$39.99 $0.09 mg/CBD
Visit Site
Score Breakdown
Quality Assurance
40/40
Hemp Quality
15/20
Extract Type
20/20
Additional ingredients
7/10
Price
8/10
CBD Amount Score IconTotal CBD 450 mg
Available Bottle Sizes Score IconUnitsNA
Potency Score IconPotency15 mg/ml

Many people prefer to use CBD capsules because of their convenience. Our top pick for anxiety is the extra strength softgels from PlusCBD, one of the first American CBD brands.

They provide 15 mg of full spectrum CBD in each softgel with 60 softgels per bottle.

 

Quality AssuranceIcon
Quality Assurance
40/40

Third party and in house tests confirm that these capsules carry the advertised amount of CBD and are free of contaminants. Additionally, PlusCBD holds the FDA’s self affirmed Generally Recognized As Safe (GRAS) status, which means its products passed rigorous safety testing.

 

Hemp QualityIcon
Hemp Quality
15/20

Unlike most American brands, PlusCBD sources its CBD from organic hemp grown in Europe. PlusCBD is also certified by the U.S. Hemp Authority.

 

Extract TypeIcon
Extract Type
20/20

These vegan friendly capsules are made with full spectrum hemp extract, providing the full benefits of hemp.

 

Additional ingredientsIcon
Additional ingredients
7/10

According to potency tests, PlusCBD’s capsules contain multiple minor cannabinoids.

 

PriceIcon
Price
8/10

PlusCBD’s softgels cost $0.08 per mg of CBD, which is on the lower end of the average cost of CBD capsules.

Pros: Cons:
  • U.S. Hemp Authority certified
  • Third party and in house testing
  • Relatively low strength

Best Gummies — Fab CBD

Fab CBD CBD Chews

Overall Score
Product Review
87out of 100
$59 $0.08 mg/CBD
Visit Site
Score Breakdown
Quality Assurance
40/40
Hemp Quality
17/20
Extract Type
12/20
Additional ingredients
10/10
Price
8/10
CBD Amount Score IconTotal CBD 750 mg
Available Bottle Sizes Score IconUnitsNA
Potency Score IconPotency25 mg/ml

If you’re after the delicious convenience of gummies, we recommend Fab CBD. The company’s fruit flavored chews carry 25 mg of pure CBD per piece, with 30 gummies per container.

 

Quality AssuranceIcon
Quality Assurance
40/40

Third party tests confirm that these gummies are free of contaminants and contain an accurate amount of CBD.

 

Hemp QualityIcon
Hemp Quality
17/20

The CBD is sourced from organic hemp grown in Colorado.

 

Extract TypeIcon
Extract Type
12/20

Like most gummies, these sweets are made with pure CBD isolate.

 

Additional ingredientsIcon
Additional ingredients
10/10

These gummies are free of artificial sweeteners and made with organic, vegan friendly ingredients.

 

PriceIcon
Price
8/10

Fab CBD’s gummies cost $0.08 per mg of CBD, which is close to the average price for CBD gummies.

Pros: Cons:
  • Medium strength potency
  • Comprehensive third party testing
  • Only one container size

Best Vape Product — CBDfx Terpene Vape Liquid

CBDfx Platinum Rose – CBD Terpenes Oil - 500 mg

Overall Score
Product Review
82out of 100
$69.99 $0.14 mg/CBD
Visit Site
Score Breakdown
Quality Assurance
40/40
Hemp Quality
15/20
Extract Type
12/20
Additional ingredients
7/10
Price
8/10
CBD Amount Score IconTotal CBD 500 mg
Available Bottle Sizes Score IconBottle Size 30 ml
Potency Score IconPotency16.67 mg/ml

For those who need immediate anxiety relief, vaping CBD can be a fast-acting alternative to CBD oil. Our top pick is the terpene vape liquid from CBDfx, which comes in four flavors and two potencies: 500 mg (17 mg/ml) and 1000 mg (33 mg/ml).

It contains a blend of terpenes inspired by popular cannabis strains. CBDfx also sells a vape kit if you don’t have a vape.Quality Assurance
Third-party tests confirm that this vape juice contains the advertised amount of CBD.

 

Quality AssuranceIcon
Quality Assurance
40/40

Third-party tests confirm that this vape juice contains the advertised amount of CBD.

 

Hemp QualityIcon
Hemp Quality
15/20

CBDfx uses organic Kentucky hemp to make its products.

 

Extract TypeIcon
Extract Type
12/20

CBDfx’s vape juice contains pure CBD isolate.

 

Additional ingredientsIcon
Additional ingredients
7/10

This vape juice contains a blend of terpenes from one of four cannabis strains. Terpenes add flavor and may have beneficial properties.

 

PriceIcon
Price
8/10

CBDfx’s terpene vape liquid costs $0.07-0.10 per mg of CBD, which is cheaper than most CBD vape oils.

Pros: Cons:
  • Most reputable CBD vape vendor
  • Multiple flavors
  • Added terpenes
  • CBD vape kit available
  • Not full-spectrum

How to choose the best CBD for anxiety

It can be difficult to choose a CBD product for anxiety with so many options. We put together some tips to help you make an educated choice:

  • Third party testing: Reputable brands send their products for testing at an independent lab to verify their safety and CBD content. You should only buy third party tested products.
  • Consumption method: CBD can be taken in different ways, each with its advantages and weaknesses. For example, some people prefer to vape CBD because it offers instant effects.
  • Type of CBD: There are three types of CBD; isolate, full spectrum, and broad spectrum. Full spectrum is considered the most effective but some people may prefer the other two types.
  • Dosage: The right amount of CBD is different for everyone. You should start with a small dose and raise it slowly. The next time you buy CBD, you can match your dosage to the optimal product potency.

We have a detailed guide for a full explanation of how to find reputable CBD companies and choose the best product for yourself.

Safety and side effects

CBD has been extensively studied, and the results suggest that it’s a safe and well tolerated compound. While it can cause some side effects, they’re usually minor, and include:

  • Tiredness and drowsiness
  • Diarrhea and nausea
  • Low blood pressure
  • Lightheadedness
  • Changes in appetite or weight
  • Dry mouth

CBD can also interact with prescription medications. The good news is that these effects were only reported by studies using high doses of pure CBD. As such, they’re not likely to happen for most people.

Still, we recommend consulting your doctor or another qualified healthcare professional before using CBD, especially if you’re taking prescription medicine.

Legality

CBD products derived from hemp (cannabis containing 0.3% or less THC) are legal under federal law in the United States. However, you also have to consider individual state laws. For example, some states ban CBD entirely or only allow products with zero THC.

You can also take CBD while driving. However, if you use a full spectrum product, you may have a detectable amount of THC in your body. That means you can test positive for marijuana if you get pulled over in a state where it’s illegal.

ENJOY READING? SHARE THIS ARTICLE
About The Authors
Gleb Oleinik
Gleb Oleinik
CBD Journalist
Gleb Oleinik is a freelance health writer and Journalist from Vancouver, Canada. He’s read thousands of research studies about various supplement ingredients, enabling him to translate complex health information into simple language. Gleb specializes in CBD and has personally tried and reviewed dozens of CBD products. He’s knowledgeable about the ins and outs of the CBD industry as well as the science and research behind this popular natural remedy.
Eloise Theisen
Eloise Theisen
RN, MSN, AGPCNP-BC
Eloise Theisen is a board certified Adult Geriatric Nurse Practitioner who specializes in cannabis therapy. For over 20 years, Eloise has worked primarily with cancer, dementia and chronic pain patients. In the last 6 years, Eloise has focused her efforts on cannabinoid therapies. Eloise has worked with over 6500 patients to help them effectively treat age-related and chronic illness with cannabis.
FOLLOW US
Important Disclaimer
All contents of the LeafReport Site, such as text, graphics, images, and other material contained on the LeafReport Site are for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on the LeafReport Site!